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Tests of nerve function with ageing

Tests of nerve function with ageing

Overview

An experiment looking at the effect of nerve function on strength as we grow older.

  • 30 Minutes
  • Research Participant
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Taking Part

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Aim

This project was initiated by the need to develop a new method for following the clinical course of patients with diseases resulting in loss of motor units, particularly motor neuron disorders (MND), and how this compares to healthy people.

This is part of a multi-hospital study which aims to examine the validity of a new test for nerve function among different doctors at different hospitals across the world.

Results from the study will have the following impact:

  • If validated, the new method will improve diagnosis and monitoring of neuromuscular disorders, i.e. MND.
  • Validation of this method will enable its use as a marker for MND and future research.

Volunteer Criteria

Researchers are seeking healthy participants between the ages of 40 and 80. In order to fulfil specific age groups, they will only be able to accept a small number of individuals at each age.

EXCLUSION CRITERIA

If you have any of the following, you must not take part:

  • You have ever been diagnosed with neurological disease
  • You have ever been diagnosed with cancer, diabetes, or nerve problems
  • Any carpal tunnel or ulnar nerve problems, or any surgery to the spine
  • Currently pregnant
  • You have a pacemaker

What will I be asked to do?

You will attend 1 appointment (on a Monday) lasting up to a maximum of 30 minutes, during which small electrical pulses made by a machine are used to mimic the electrical signals made by nerves in turn to your wrist. Recordings will be taken from your hand.

This process is not painful, but might be slightly uncomfortable.

Three recordings, each around 5 minutes, will be performed. These might need to be repeated if there are any problems.

During each recording, you will be asked to remain as still as possible to reduce any movement on the recording.

When and where?

You will be required to attend 1 appointment (on a Monday) lasting a maximum of 30 minutes.

Researchers will arrange appointments with each individual participant.

The experiment will take place at:

The Henry Wellcome Building,
Newcastle University Medical School,
Framlington Place,
NE2 4HH.

Enter the main medical school entrance, turn left, and continue down the corridor for about 50m. The entrance is on the left and clearly marked.

Will I get anything for taking part?

Reasonable travel expenses will be reimbursed as required to attend this experiment.

Location

Henry Wellcome Building, Newcastle University Medical School
Framlington Place
Newcastle upon Tyne
Tyne and Wear
NE2 4HH

Newcastle University

Owners

Taking Part

To register your interest in taking part in this opportunity, please click the button below.

By doing this you agree to sharing your details with the opportunity owner.

I would like to take part

Tests of nerve function with ageing Discussion

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phil_om

phil_om

2nd September 2022

I am aged 80 and have an essential tremor in both hands is this likely to exclude me 

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StuMaitland

StuMaitland

2nd September 2022

Thank you for enquiring,

Apologies however your essential tremor is likely to limit the reliability of the recordings we perform, therefore you would not be suitable for this study. Please note this doesn't affect your suitability for future studies which have their own criteria.

Kindest regards

Stuart

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phil_om

phil_om

2nd September 2022

Thank you for your quick response. 

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