Brain mechanisms of Post-COVID19 fatigue: New study recruiting in London
The aim of this study is to understand whether neuroinflammation might play a role in persistent fatigue after COVID-19. To do this we will use state-of-the-art brain imaging techniques to see how brain structure, function and chemistry differs between people that had COVID-19 and continue experiencing fatigue versus those that do not experience fatigue.
This will help us understand more about the illness itself and how we might be able to treat it better.
We will recruit people who are currently experiencing persistent high levels of fatigue and people whose symptoms resolved and do not experience fatigue post-COVID-19.
We are inviting people:
- who had COVID-19 between 3 - 12 months ago*
- are between 16 - 65 years old
- did not suffer from persistent fatigue before COVID-19 infection
Please review the full eligibility on the study website.
*Please note: we are looking to widen the criteria to allow the inclusion of people who had COVID-19 more than 12 months ago; if this is the only criteria you do not meet, please do get in touch because we might be able to enrol you later on.
What will I be asked to do?
Taking part in the study involves 1 screening session by phone and 1 visit to the Centre for Neuroimaging Sciences, Kings College London at Denmark Hill. These sessions will be spread over a period of a minimum of approximately 5 days and a maximum of 2 weeks.
- Screening interview: A screening session by phone to assess whether you are suitable for the study.
- Study visit: An imaging visit where you will have an MRI scan to assess your brain and 1 blood sample which we will use to isolate plasma and assess the levels of peripheral inflammation in your blood. We will also assess your symptoms with questionnaires and ask you to provide a urine sample, which we will use for drug and pregnancy (in case of women) testing.
- Online questionnaires: We will also ask you to fill in some self-report questionnaires online within 72h after you have completed the study visit these questionnaires will last for about 45 mins and you can take as many breaks as you need).
When and where?
King’s College Hospital, Denmark Hill, London and online
Will I get anything for taking part?
A fixed amount of 50£ will be paid to everyone to cover time and expenses
This research has received ethical approval: 22/SW/0068
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