Health & Social Care Research

PriMUS Study Management Group

PriMUS Study Management Group
  • Public/Patient Representative
  • Influence

An opportunity to join the study management group for the PriMUS study.

The date given above is the deadline for applications. Dates and times for the study management group will be confirmed with successful applicants.

Primary care Management of lower Urinary tract Symptoms in men (PriMUS): Development and validation of a diagnostic and decision-making aid.

Lay Summary

More than 10% of older men experience the need to pass urine more frequently than usual and often find their sleep interrupted by having to go to the toilet at night. Some will find that their urine flow rate has become slower, and some will experience loss of bladder control. Such problems are distressing for men and are a common reason why men visit a general practitioner (GP), with over 60,000 attendances yearly across the UK. They firstly need reassurance that they are not suffering from cancer or any other sinister medical condition. GPs follow established procedures when considering signs of cancer or these more serious conditions, but they have no easily available assessment tools to identify other more common causes of lower urinary tract symptoms (LUTS), or to advise men about the best treatment options for symptom relief.

Because of this, men have to be referred to hospital based urology specialists for tests and diagnosis. We aim to establish a practical and accurate decision aid for use by GPs to diagnose the cause of LUTS in men and to assist decisions in determining appropriate person-centred treatment. Successof the study will benefit men with LUTS, general practice and the wider health system by:

  • Reducing waiting times before men are assessed and diagnosed
  • Giving men early access to appropriate treatment plans personalised to them
  • Reducing the number of men needing referral to hospital based urology specialists
  • Early referral of those men with more complex problems to specialist urology services

The study will demonstrate if a set of simple test results can be incorporated into a computer software programme for use by GPs to establish a diagnosis of the cause of LUTS in an individual and therefore guide selection of appropriate treatment options to relieve symptoms. With the help of general practices across the UK, we will recruit 880 men with LUTS into the study. The tests will include men keeping a diary for a few days to record the timing and amount of urine passed, measuring urine flow with a small portable machine, and asking men to complete symptom questionnaires. To assess the performance and accuracy of the tests, all men in the study will also need to have a more complicated test done by a specially trained nurse. This special test is called urodynamics and involves the passing of a thin tube into the bladder through which the bladder is then filled with water. A thin rectal catheter is also needed to control for changes in abdominal pressure. By comparing results of the simple tests with results of urodynamics we will identify which simple tests give best agreement. The top performing simple tests will then be incorporated into development of the decision making aid. The decision aid will be presented to GPs in a format that allows them to enter test results and then get a read out of the diagnosis and recommended treatment. The study will also consider practicalities for both patients and clinical staff in doing the simple tests in the general practice setting, and the ease with which the decision making tool can be used. The study is being run by Cardiff University in collaboration with other groups around the UK.

PriMUS Study Management Group Location
Get In Touch

VOICE at Newcastle,
The Catalyst, 3 Science Square,
Newcastle upon Tyne, NE4 5TG