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Important outcomes for trials to stop medicines where the chance of harm outweighs benefit

Important outcomes for trials to stop medicines where the chance of harm outweighs benefit

Overview

Help to develop a set of the most important things to look at in trials of stopping medicines.

  • 15 minutes
  • Questionnaire
  • Participate

Taking Part

This opportunity has already taken place

Aim

Nine out of ten patients and carers believe that medicines that may cause harm or discomfort should be stopped in hospital. We however, know that this rarely happens.

CHARMER (CompreHensive geriAtRician-led MEdication Review) is a group of studies designed to develop an approach to increasing the chances of medicines that may cause harm or discomfort in the future being stopped when people are in hospital.

To see if our approach works, we need to know what ‘works’ means and so we need to decide what this is and how to measure it. For example, one of the things to look at might be about not feeling tired and sleepy anymore after stopping a medicine and so we may want to measure ‘how tired’ a person is. This part of the CHARMER study is about deciding what we should be measuring to check that our approach is both safe and effective.

We will ask people aged 65 years and over who are taking 5 or more prescribed medicines, and their family members, healthcare staff and other experts to help us with this. We want to find out what is important to look at when stopping medicines that are doing more harm than
good.

Everyone who takes part in the study will be asked to look at a list of things that could be measured. They will be asked to give each of these measures a score between 1 (not
important) and 9 (very important). Scores in between 1 and 9 mean that the measure has some importance.

Once we have the scores from those who take part, we will work out which things are important for us to measure. Those that are rated the most important will then be used in our study when we develop and test our approach. We will share this list of important things to measure with other researchers doing similar studies. This means that everyone is then looking at the same things.

Volunteer Criteria

To take part you must be:

  • Aged 65 or over, taking 5 or more prescribed medicines and living in England
  • OR a relative or friend who helps someone aged 65 and over with their medicines

What will I be asked to do?

You will be asked to take part in 3 online questionnaires over a period of 2-3 months. The questionnaires list possible outcomes we could measure when stopping medicines that are no longer working or may be causing harm. We ask people to tell us how important each outcome is for them on a scale of 1 (not important) to 9 (critical), with an 'unable to rate' option for any outcome they are unsure how to score.

Each questionnaire will take approximately 15 minutes to complete.

When and where?

You can complete the first questionnaire either online or via telephone any time until 14th June 2021.

Participant Information Sheet

Newcastle University

Taking Part

This opportunity has already taken place

Important outcomes for trials to stop medicines where the chance of harm outweighs benefit Discussion

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