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Appetite and Ageing

Appetite and Ageing

Overview

Researchers are interested in how the hormonal regulation of appetite and hunger is affected with ageing.

  • 2 days
  • Research Participant
  • Participate

Taking Part

To register your interest in taking part in this opportunity, please click the button below.

By doing this you agree to sharing your details with the opportunity owner.

This opportunity closes at midnight on the 29th of October 2022

I would like to take part

Aim

The aim of this study is to better understand how hormonal regulation of appetite changes with ageing.

 As we age, it is common to perceive a reduction in appetite. This can lead to a reduction in food intake – typically, those over 65 years consume 30% less energy than younger adults – which can result in insufficient energy and protein intake. Protein and energy malnutrition is a contributor to loss of muscle and strength, which can lead to frailty in later life.

This research aims to determine if older adults, and particularly older adults who are experiencing appetite loss, have differing levels of, and responses to, the hunger hormone ghrelin. A better understanding of how ageing effects this hormone will inform potential treatments to overcome severe loss of appetite and insufficient food intake in later life. If they are successful in this pursuit, this will slow down rates of muscle loss and the onset of frailty, improving quality of live in advancing years.

Researchers are looking for those over the age of 65 years to take part in their study. If you are of low-to-moderate activity level (i.e., don’t partake in regular exercise more than once a week), are of at or below a healthy weight, do not have any food allergies and do not have a phobia of blood or needles, then they would love to hear from you.

Volunteer Criteria

Incluscion criteria

  • Aged 65 years and older
  • Low-to-moderately active (i.e., do not exercise more than once a week)
  • At or below your ideal weight (a BMI of below 32 kg/m2)
  • Free from cardiometabolic disease, such as heart disease or diabetes
  • Are not intentionally trying to lose weight
  • Do not have any food allergies
  • Do not smoke
  • Comfortable with providing blood samples

If you meet this criteria, please apply

What will I be asked to do?

Participants will be asked to visit the Human Nutrition Laboratory on two occasions.

First Visit (30 Minutes):

  • Ensure you are fully aware of what pariticipation in the study will ential and answer any questions you have, before providing your consent to partake.
  • Measure your height and weight.
  • Complete two questionaires relating to your eating, health, and general questions about your medical history to ensure you are safe and able to take part.
  • The visit will finish with an explanation of what will happen on your next visit, and you will be given a food diary to take home.

Second visit (5.5 hours):

  • Arrive at the Human Nutrition Laboratory in the morning, after an overnight fast and abstaining from exercise and caffeine.
  • A cannula will be inserted into a vein in your arm, allowing a number of blood samples to be taken throughout the trial.
  • A small blood sample will be taken and you will be asked to rate your appetite, before being provided with breakfast (porridge oats, skimmed milk, yoghurt and honey (470kcal)).
  • You will then rest for a period of 4-hours with blood samples and apetite rating being taken at the 0.5, 1, 1.5, 2, 3 and 4-hour time points.
  • After 4 hours, the cannula will be removed and your will be given a pasta and sauce lunch meal, before leaving with a food diary to keep for the rest of the day.

When and where?

Human Nutrition Laboratory at Newcastle University, Dame Margaret Barbour Building

Data collection ongoing until October 2022.

Dates of your visit will be discussed with the researcher.

Will I get anything for taking part?

Participants will receive full financial reimbursement for travel to and from the University.

As part of the study, researchers will use sophisticated equipment and methods to obtain interesting data which they will share and interpret with participants (sharing with you only your own data). As well as measuring the hunger hormone ghrelin, which will provide unique insight into how your body regulates your hunger, they will measure body composition (the amount of fat and muscle you have in your body) and will use a sophisticated software programme to assess dietary intake. They will thoroughly analyse body composition and dietary intake data, providing you with an interpretation and short report on what this data means.

Location

Dame Margaret Barbour BUilding
Wallace Street, Richardson Road
Newcastle upon Tyne
Tyne and Wear
NE2 4DR

Newcastle University

Taking Part

To register your interest in taking part in this opportunity, please click the button below.

By doing this you agree to sharing your details with the opportunity owner.

This opportunity closes at midnight on the 29th of October 2022

I would like to take part

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