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An Observational Study of Interoceptive Awareness in Migraine

An Observational Study of Interoceptive Awareness in Migraine

Overview

This study is aiming to better understand the cause and purpose of migraine.

  • 1 hour
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Taking Part

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I would like to take part

Aim

Migraine is typically characterised by a throbbing pain that intensifies sporadically. The pain is often debilitating, and often involves associated symptoms such as nausea, vomiting, visual distortion, photophobia (light sensitivity) and phonophobia (noise sensitivity). We hope that gaining a more complete understanding of the purpose and cause of migraine will lead to new treatment approaches in future.

This study is aiming to better understand the cause and purpose of migraine, by studying its relationship to a process called interoception.

Interoception is described as the perception of sensations from inside the body. Physical sensations include heartbeat, respiration, hunger and the autonomic (fight-or-flight) nervous system. Interoception also interacts with external sensations (such as hearing and vision) thought, emotion and psychology.  This study will measure subjective and objective aspects of interoception, and its association with migraine symptoms.

This study will measure subjective and objective aspects of interoception, and its association with migraine symptoms. The aim is to establish whether there is a link between certain aspects of interoception and how often migraine attacks occur. If such links are found, it may lead to an improved understanding of the cause of migraine.

 

Volunteer Criteria

Inclusion criteria:

  • Age 18 or over
  • The ability to make and communicate an informed choice about whether to take part in the study
  • The ability to sit still and comfortably in a comfortable chair for around 1hour
  • Experience recurrent migraines

 

Exclusion criteria:

  • Headache that is so persistent that you never, or only rarely, have days where you do not have some kind of headache.
  • Currently taking continuous migraine preventative medication (this does not include reactive medication which is only taken when you feel a migraine about to start)
  • The ongoing use of sedating medications, or certain other nerve-acting or antidepressant medications
  • Any abnormality of brain structure (e.g. stroke, tumour), or other neurological disorder (e.g. multiple sclerosis or epilepsy)
  • A current mental health condition of sufficient severity to prevent certain activities of everyday life.

What will I be asked to do?

The first stage is to complete a pre-screening questionnaire, which will help to determine whether you are eligible to take part. This will be shared with you by the researcher, via email, after you have applied to the opportunity.

If you are eligible to take part, then the main study involves one visit to the study centre in Newcastle University Medical School which will involve the following:

  1. Further discussion of the study, and signing of a consent form 
  2. To complete a second, more detailed, questionnaire assessing the following:
  • Body Perception
  • How migraine affects your day to day life on a physical, emotional and social level
  • General mood and wellbeing
  • How you feel in, and respond to, uncertain situations
  1. An electroencephalography (EEG) session.
    In this, a fabric cap is placed over your head, and a number of spots of gel placed in this (a similar consistency to hair gel, which will remain in your hair until washed out with water). This cap records the electrical signals your brain naturally generates. The most important things you need to do during the EEG session are to stay awake, keep your eyes open, and keep your head, face, neck and body in a relaxed state. Setup takes around 30 minutes, and then you will perform the following stages:
    • 10 minutes of ‘resting state’, in which you sit relaxed and looking ahead
    • 10 minutes of a heartbeat monitoring task. This will be broken up into short sections of around 30-60 seconds, and you simply need to try to sense your heartbeat, and count how many beats occur during that time
    • 10 minutes of measuring the brain’s response to sounds. During this a series of beeps will be played through headphones. 

When and where?

Institute of Neuroscience
Newcastle University Medical School
Framlington Place,
Newcastle upon Tyne,
NE2 4HH.

This research will run from April - December 2022

Will I get anything for taking part?

£10 plus reimbursement of any travel expenses

Location

The Medical School
Framlington Place
Newcastle upon Tyne
Tyne and Wear
NE2 4HH

Newcastle University

Owners

Taking Part

To register your interest in taking part in this opportunity, please click the button below.

By doing this you agree to sharing your details with the opportunity owner.

I would like to take part

An Observational Study of Interoceptive Awareness in Migraine Discussion

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Ianeon

Ianeon

23rd September 2022

I think that migraines are pains which tell you that there is a problem in your body.                                                                                                                           They don't tell you what is wrong in your body or how to treat the problem.                                               
I'm not clever enough to understand if these pains are the result of physical or mental problems or both.                                                                                                  So I don't know who should treat migraines :(

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