REACT: COVID-19 Community Network
Join this Group to receive news updates and invites to events and involvement opportunities relating to Imperial’s REACT COVID-19 and Long COVID research.
About this group
This network was formed by Imperial’s Patient Experience Research Centre (PERC) to help ensure a wide and diverse range of perspectives and experiences can continue to inform what we learn about COVID-19 through Imperial’s REACT study. REACT (REal-time Assessment of Community Transmission) started out in May 2020 as the biggest study of coronavirus and antibody self-testing in England and has played a critical role in tracking the outbreak ever since. But with over 2 million having now taken part, the REACT study also represents something unique – an enhanced dataset and cohort of people that can help us better understand the social, environmental, biological and genetic risk factors for COVID-19 and Long COVID, as well as the health and emotional impact experienced by people and society. That’s because participants were selected at random making this a highly diverse and representative sample of England that includes people who have or have not had COVID and those who did or did not get symptoms.
Since COVID-19 emerged, PERC have sought to put community voices at the heart of Imperial’s research. The REACT Public Advisory Group (PAG) was set up to embed public, patient and participant voices into the design and development of REACT, from the start. Their input has been, and continues to be, invaluable. But as the research enters a new phase where more voices and perspectives are needed to help us understand the short and long-term health impacts of COVID-19, our approach to public engagement and involvement needs to evolve too, which is why we opened this public network.
It is open to anyone wishing to support or stay updated about Imperial’s ongoing research, particularly if you have been affected by COVID-19, experienced ongoing ill health and/or were a participant in the REACT study.
All members will need to adhere to our Code of Conduct.
Here is an outline of current research activity relating to REACT, with links to study websites where you can learn more. Members of this network will receive updates about any upcoming engagement events or tailored invites to to be involved in this or related COVID-19 research activity at Imperial, as well hear about the latest findings as they come out.
REACT (REal-time Assessment of Community Transmission) Study
What: A series of studies that are using at-home coronavirus testing (REACT-1) and antibody testing (REACT-2) to improve our understanding of how the COVID-19 pandemic is progressing across England and how many have developed antibodies after infection or vaccination.
Who: Participants in England are sampled at random from the NHS database. Each round involves between 120,000-170,000 people with over 2 million people having taken part to date.
When: May 2020 to January 2022
This research was commissioned by the Department of Health and Social Care (DHSC) and is being carried out by Imperial College London in partnership with Ipsos MORI and Imperial College Healthcare NHS Trust.
REACT-LC (REACT-Long COVID) Study
What: Using health surveys and in-depth interviews alongside clinical and biological assessments (including genetic sequencing) to identify and understand the social, environmental, biological and genetic factors involved in the development and duration of Long COVID, as well as lived experience.
Who: Previous REACT participants who consented to be invited to future research and data linkage
When: March 2021 to February 2024
This project was funded by National Institute for Health Research and UK Research & Innovation (UKRI) and is being carried out by Imperial College London in partnership with Queen Mary University of London, the Francis Crick Institute, Leiden University, Southampton University, Birmingham University and Newcastle University.
REACT-GE (REACT-Genomic) Study
What: Using health surveys alongside clinical and biological assessments (including genetic sequencing) to identify and understand the biological and genetic factors that determine whether or not someone becomes severely ill and/or experiences ongoing illness after COVID-19.
Who: Previous REACT participants who consented to be invited to future research and previously tested positive to either COVID-19 or antibodies
When: December 2021 to June 2021
This project was funded by UK Research & Innovation and is being carried out as a partnership between Imperial College London, who lead the REACT study, and Genomics England, who are leading a study called GenOMICC.
REACT Data Linkage Project
What: Link the REACT research records to participant’s NHS health records (e.g., GP records) to better understand the risk factors for COVID-19 and ongoing ill health, understand the healthcare needs of those affected by COVID-19, and inform future public health planning and the ongoing outbreak response.
Who: REACT participants who consented to data linkage
When: January 2021 to June 2021
This project was funded by Health Data Research UK as part of their Data & Connectivity National Core Study ambitions, which aim to enable greater impact from currently funded UKRI and DHSC COVID-19 research.
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