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Weight loss puts Type 2 diabetes into remission for at least two years

More than a third of people with Type 2 diabetes who took part in a weight management programme delivered by the NHS through GP surgeries remain free of diabetes two years later.

These latest findings of the Diabetes Remission Clinical Trial (DiRECT), funded by Diabetes UK and led by experts at Newcastle University and the University of Glasgow, were announced today at Diabetes UK’s Professional Conference and published in The Lancet Diabetes & Endocrinology.

Professor Roy Taylor from Newcastle University, who co-led the trial, said the findings “pull down the curtain on the era of Type 2 diabetes as an inevitably progressive disease.”

These new results build on the globally-reported findings of December 2017, which showed that 46% of participants were in remission after one year. A year later, 70% of those participants are still in remission.

The results confirm that remission is closely linked to weight loss; 64% of participants who lost over 10 kilos (1 stone 8 lb) were in remission after two years. Participants regained some weight, as the researchers expected, between the first and second year. However, those in remission after one year who stayed that way had a greater average weight loss (15.5 kilos) than those who did not stay in remission (12 kilos).

Participants were defined as in remission if they had long-term blood glucose levels (HbA1c) of less than 48mmol/mol (6.5%) without needing to use any Type 2 diabetes medications.

 

To read the full article please visit the Newcastle University website. 

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